This project focused on simulating and assessing the performance of Howorth’s ExFlow 28 Evolution Ultra-Clean Ventilation (UCV) system within a representative operating theatre. Using advanced Computational Fluid Dynamics (CFD) techniques, a detailed three-dimensional digital model was created to capture airflow patterns, velocity fields, and air exchange pathways between the theatre and its surrounding spaces. The model incorporated critical features such as pressure stabilisers, transfer grilles, exhausts, and door gaps, ensuring realistic boundary conditions and highly accurate results. A high-resolution mesh enabled precise prediction of complex flow behaviour, while validation against experimental measurements confirmed the robustness of the simulations. The study not only demonstrated compliance with stringent air quality and velocity criteria but also provided clear visualisations—using contours, vectors, and streamlines—to support stakeholder decision-making. This work highlights our capability to deliver advanced CFD models for system optimisation, performance validation, and future product development