We optimised a ventilation grille’s lattice geometry to improve airflow distribution while minimising pressure loss. A targeted computational fluid dynamics model of the grille and the near‑field duct section resolved jet formation through each lattice and recombination downstream. The study swept cell shapes, open‑area ratios and bar thickness and spacing to quantify trade‑offs between lattice design optimisation and manufacturability. Metrics included system loss coefficient, flow‑uniformity indices at defined sampling planes and sensitivity to installation misalignments expressed in engineering terms. Mesh and solver checks ensured stable option‑to‑option trends, and parametric runs established response surfaces to guide selection. The preferred lattice achieved better HVAC flow distribution without a significant head‑loss penalty, particularly when small fillets and moderated porosity gradients were introduced to suppress separation and equalise velocities. We recommended a geometry that delivers robust uniformity across realistic operating envelopes, supported by simple dimensional tolerances to protect performance during fabrication and installation.